Journal article
The efficacy and safety of nutrient supplements in the treatment of mental disorders: a meta-review of meta-analyses of randomized controlled trials
J Firth, SB Teasdale, K Allott, D Siskind, W Marx, J Cotter, N Veronese, F Schuch, L Smith, M Solmi, AF Carvalho, D Vancampfort, M Berk, B Stubbs, J Sarris
World Psychiatry | WILEY | Published : 2019
DOI: 10.1002/wps.20672
Abstract
The role of nutrition in mental health is becoming increasingly acknowledged. Along with dietary intake, nutrition can also be obtained from “nutrient supplements”, such as polyunsaturated fatty acids (PUFAs), vitamins, minerals, antioxidants, amino acids and pre/probiotic supplements. Recently, a large number of meta-analyses have emerged examining nutrient supplements in the treatment of mental disorders. To produce a meta-review of this top-tier evidence, we identified, synthesized and appraised all meta-analyses of randomized controlled trials (RCTs) reporting on the efficacy and safety of nutrient supplements in common and severe mental disorders. Our systematic search identified 33 met..
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Awarded by National Institute for Health Research
Funding Acknowledgements
J. Firth is supported by a Blackmores Institute Fellowship; J. Sarris by a National Health and Medical Research Council (NHMRC) Clinical Research Fellowship (APP1125000); M. Berk by a NHMRC Senior Principal Research Fellowship (APP1059660 and APP1156072). B. Stubbs holds a clinical lectureship supported by Health Education England and the National Institute for Health Research (NIHR) Integrated Clinical Academy Programme (ICA-CL-2017-03-001). K. Allott is supported by a Career Development Fellowship from the NHMRC (APP1141207). D. Siskind is supported in part by an Early Career Fellowship from the NHMRC (APP1111136). W. Marx is supported by a Deakin University postdoctoral fellowship. The views expressed in this paper are those of the authors and not necessarily those of the above-mentioned entities.